The T-SPOT.TB test advantages

The T-SPOT.TB test is the only globally regulated IGRA available that is normalised for both cell number and culture conditions. The test standardises the number of cells and removes serum factors that could adversely affect the test result, making it the most sensitive and most specific test for TB infection2,3 .

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T CELLS MATTER

When your test looks for signs of TB infection using T cells, it matters how many T cells you include. The T-SPOT.TB test, unlike other tests, uses the same number each time. And it’s a big number: 250,000 cells per well, four wells per test2. That’s a million witnesses to infection – and a moment of truth for TB.

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The T-SPOT.TB test is a unique, single visit blood test for tuberculosis designed to reduce assay variability and maximise sensitivity, even in the immunosuppressed2

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T Cells Matter

When your test looks for signs of TB infection using T cells, it matters how many T cells you include. The T-SPOT.TB test, unlike other tests, uses the same number each time. And it’s a big number: 250,000 cells per well, four wells per test.2 That’s a million witnesses to infection – and a moment of truth for TB.

TECHNOLOGY

Isolate PBMCs

Enriches the desired cell population
(T cells) from whole blood

Wash cells

Enables removal of serum and potentially interfering substances

Standardise cells

Ensures that the required number of cells are used to produce a reportable result

Direct visualisation

Single cell readout gives us the number of responsive cells

Technology

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